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The key role of Dkk1 gene in cancer development and its potential therapeutic applications

from EIAab

Abstract:Dkk1 DICKKOPF-1 gene, as a member of the Dickkopf family, has attracted extensive attention in the field of cancer research in recent years. In this paper, the molecular structure and function of Dkk1 gene and its important role in tumor development were discussed in detail. Dkk1 regulates a variety of cell bi...

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02 / 02

2024

CDH13 (cadherin 13) : New perspectives on neurodevelopment and neurological diseases

from EIAab

CDH13 cadherin 13 : New perspectives on neurodevelopment and neurological diseasesAbstract:CDH13, or cadherin 13, is a transmembrane cell adhesion protein that was originally extensively studied in heart development. However, research in recent years has revealed the key role of CDH13 in the nervous system. This articl...

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10 / 31

2023

B2m, Protein, ELISA Kit, Antibody

from EIAab

B2m is a protein that is widely present in the body and plays an important role in the immune system. The protein encoded by this gene is β2 microglobulin, which is a small molecule protein with a molecular weight of approximately 12 kDa. β2 microglobulin is one of the important components of the immune system,...

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10 / 07

2023

Immune Response and Sec-Immunodeficiency with IL-6 Expression: An emerging epidemic in urban populations.

from EIAab

IL-6 is a signaling protein involved in the maintenance of the immune system. It plays a crucial role in regulating host immunity, signalling multiple immunity response genes, and involved in host cellular morphology and function. In the present study, we investigated the relationship between immune response an...

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06 / 07

2023

Ninj2 Gene: A Potential Therapeutic Target for Neurodegenerative Diseases

from EIAab

Abstract:Neurodegenerative diseases, such as Alzheimer's and Parkinson's, are characterized by the progressive loss of neurons in the brain. Currently, there are no effective treatments for these diseases. The Ninj2 gene has been identified as a potential therapeutic target for neurodegenerative diseases. This ...

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05 / 30

2023

C19orf80 gene: A key Y chromosome gene regulatory element

from EIAab

This article will focus on the C19orf80 gene, a key gene regulatory element found on the Y chromosome. The C19orf80 gene plays an important role in mammalian sex determination and development by participating in transcriptional regulation and the generation of cluster non-coding Rnas. In this paper, the structure, func...

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05 / 16

2023

IL-17 stimulation induces NOTCH1 activation in OPC, leading to Th17-mediated demyelinating disease

from EIAab

Multiple sclerosis Multiple sclerosis is a central nerve demyelination disease, which is more common in Western countries, and the number of cases in my country is also increasing year by year. The disease usually presents the characteristics of remission and recurrence course, and it usually occurs in the optic nerve,...

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05 / 21

2022

Basigin Antibodies with Capacity for Drug Delivery Across Brain Endothelial Cells

from EIAab

The blood-brain barrier BBB poses challenges for delivering antibody-based therapeutics to the brain and is a main obstacle for the successful application of biotherapeutics for the treatment of brain disorders. As only a small fraction of monoclonal antibodies mAbs is penetrating the BBB, high doses of therapeutics ar...

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04 / 06

2022

Potential new targets for the treatment of obesity and metabolic related diseases

from EIAab

Obesity and related metabolic diseases, including type II diabetes, cardiovascular disease and cancer, seriously threaten human’s health. The occurrence of obesity is mainly caused by energy imbalance, so increasing the body's energy expenditure can effectively inhibit the occurrence of obesity. The brown adi...

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04 / 02

2022

Caspase-2 enzyme inhibitor can improve fatty liver disease

from EIAab

Dr. Michael Karin, a professor at the University of California San Diego School of Medicine, found through mouse and human clinical specimens that caspase-2, a proteolytic enzyme, is a key driver of non-alcoholic steatohepatitis NASH.In the latest study, the researchers first stimulated NASH-like diseases by combining ...

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03 / 02

2022

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