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Abstract:Dkk1 DICKKOPF-1 gene, as a member of the Dickkopf family, has attracted extensive attention in the field of cancer research in recent years. In this paper, the molecular structure and function of Dkk1 gene and its important role in tumor development were discussed in detail. Dkk1 regulates a variety of cell bi...
02 / 02
2024
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from   EIAab
CDH13 cadherin 13 : New perspectives on neurodevelopment and neurological diseasesAbstract:CDH13, or cadherin 13, is a transmembrane cell adhesion protein that was originally extensively studied in heart development. However, research in recent years has revealed the key role of CDH13 in the nervous system. This articl...
10 / 31
2023
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4
from   EIAab
B2m is a protein that is widely present in the body and plays an important role in the immune system. The protein encoded by this gene is β2 microglobulin, which is a small molecule protein with a molecular weight of approximately 12 kDa. β2 microglobulin is one of the important components of the immune system,...
10 / 07
2023
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from   EIAab
IL-6 is a signaling protein involved in the maintenance of the immune system. It plays a crucial role in regulating host immunity, signalling multiple immunity response genes, and involved in host cellular morphology and function. In the present study, we investigated the relationship between immune response an...
06 / 07
2023
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5
from   EIAab
Abstract:Neurodegenerative diseases, such as Alzheimer's and Parkinson's, are characterized by the progressive loss of neurons in the brain. Currently, there are no effective treatments for these diseases. The Ninj2 gene has been identified as a potential therapeutic target for neurodegenerative diseases. This ...
05 / 30
2023
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5
from   EIAab
This article will focus on the C19orf80 gene, a key gene regulatory element found on the Y chromosome. The C19orf80 gene plays an important role in mammalian sex determination and development by participating in transcriptional regulation and the generation of cluster non-coding Rnas. In this paper, the structure, func...
05 / 16
2023
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from   EIAab
Multiple sclerosis Multiple sclerosis is a central nerve demyelination disease, which is more common in Western countries, and the number of cases in my country is also increasing year by year. The disease usually presents the characteristics of remission and recurrence course, and it usually occurs in the optic nerve,...
05 / 21
2022
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24
from   EIAab
The blood-brain barrier BBB poses challenges for delivering antibody-based therapeutics to the brain and is a main obstacle for the successful application of biotherapeutics for the treatment of brain disorders. As only a small fraction of monoclonal antibodies mAbs is penetrating the BBB, high doses of therapeutics ar...
04 / 06
2022
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from   EIAab
Obesity and related metabolic diseases, including type II diabetes, cardiovascular disease and cancer, seriously threaten human’s health. The occurrence of obesity is mainly caused by energy imbalance, so increasing the body's energy expenditure can effectively inhibit the occurrence of obesity. The brown adi...
04 / 02
2022
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from   EIAab
Dr. Michael Karin, a professor at the University of California San Diego School of Medicine, found through mouse and human clinical specimens that caspase-2, a proteolytic enzyme, is a key driver of non-alcoholic steatohepatitis NASH.In the latest study, the researchers first stimulated NASH-like diseases by combining ...
03 / 02
2022
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